![]() ![]() Of 9,056 diabetics enrolled, 6,544 (72%) received a behavioural support group session. Two primary outcomes were hospital admissions involving infectious diseases and culture-confirmed melioidosis. All diabetic patients were contacted by phone yearly, and the final follow-up was December 2018. We randomly allocated the PCUs to receive the intervention starting in March 2016, 20. The intervention was a behavioural support group session to help diabetic patients adopt recommended behaviours, including wearing rubber boots and drinking boiled water. More compelling invitations for the intervention, modification of or addition to the behaviour change techniques used, and more frequent intervention may be needed.Trial registrationThis trial is registered with, number NCT02089152.įrom April 2014 to December 2018, we conducted a stepped-wedge cluster-randomized controlled behaviour change trial in 116 primary care units (PCUs) in Ubon Ratchathani province, northeast Thailand. In the per-protocol analysis, patients who received a behavioural support group session had lower incidence rates of hospital admissions involving infectious diseases (incidence rate ratio 0.89 95%CI 0.80-0.99, p = 0.03) and of all-cause mortality (IRR 0.54 95%CI 0.43-0.68, pConclusions/significanceClear benefits of this multifaceted prevention programme for melioidosis were not observed. In the intention-to-treat analysis, implementation of the intervention was not associated with primary outcomes. During 38,457 person-years of follow-up, we observed 2,195 (24%) patients having 3,335 hospital admissions involved infectious diseases, 80 (0.8%) melioidosis, and 485 (5%) deaths. We aim to evaluate the effectiveness of a multifaceted prevention programme for melioidosis in diabetics in northeast Thailand.Methodology/principal findingsFrom April 2014 to December 2018, we conducted a stepped-wedge cluster-randomized controlled behaviour change trial in 116 primary care units (PCUs) in Ubon Ratchathani province, northeast Thailand. Diabetes mellitus and environmental exposure are important risk factors for melioidosis acquisition. BackgroundMelioidosis, an often-fatal infectious disease caused by the environmental Gram-negative bacillus Burkholderia pseudomallei, is endemic in tropical countries. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |